Science Is Open Software

(jepedersen.dk)

56 points | by jegp 4 hours ago

9 comments

  • D-Machine 33 minutes ago
    Science should be more like this, in current times, yes.

    But until much of academia is burned to the ground, or until science can be properly separated from modern academia, this will never be so. The current academic incentives are all wrong: low-quality research is rewarded and results in publications, whereas high-quality research (that takes time, and usually reveals that most exciting publications depend on p-hacking or other highly data-dependent analyses and selective presentations) is not published or actively blocked during peer review.

    So instead you get BS arguments about how data can't be released for various privacy concerns (when in reality the vast majority of most datasets are trivial to scrub of identifying factors, and even in more complex datasets where you need to consider k-anonymity, it is still trivial to release data that allows replication of core analyses), and academic science is increasingly irrelevant unless it is tied to tech and industry, where producing junk actually has real negative economic and personal consequences.

    I don't know what world this article / post lives in, but it isn't the messy world of actual reality.

  • flopsamjetsam 2 hours ago
    > Every result is instantly reproducible. When you read a paper claiming that a new drug reduces symptoms by 30%, you click a link and watch the exact analysis run in your browser. The data processing, statistical tests, and visualizations execute in seconds using the same environment the authors used—preserved perfectly through reproducible containers.

    At least some journals have this as a stipulation e.g. https://www.nature.com/nature-portfolio/editorial-policies/r...

    Particularly the "data availability" and "Availability and peer review of computer code and algorithm".

    However, in my limited experience, of trying to reproduce certain scRNA-seq processing pipelines, in practice it's never available as just a Github link. I can understand that some/many researcher's code is not in good shape, so I think it'll be quite a stretch to have this available.

    I do think it's laudable though, to try and make it available. It would certainly have been very useful for me in the past.

  • willtemperley 3 hours ago
    > modern science is synonymous with open source software.

    Another problem with reproducibility is the openness of the underlying data. Many academics are terrified of giving away the golden goose and the software is often useless without the data.

    However many scientists do work openly, e.g. The Journal of Open Source Software:

    https://joss.theoj.org/

  • samayashar 2 hours ago
    Nice read. I believe that traditional software is a great way to showcase the proofs when it comes to physics and mathematics. You can easily code up a theorem in a language of your choice and justify that 'Okay, the output matches the expected value'.

    I am particularly fascinated by labs like DeepMind [https://deepmind.google/science/]. The recent advances in their frontier models that are able to predict diseases before they're diagnosed is incredible. This is what AI should be built for and actually do!

    • jegp 23 minutes ago
      Thanks! I appreciate that. Your point about DeepMind and frontier models is spot on. When they "embody"/build on the science done before them we get absolutely mindblowing synergies. But I wonder what happens when the LLMs become way smarter that us: why even loop us in? I guess that's related to the recent field medalist letter https://mathandai.org/
  • random3 3 hours ago
    Science is open, but science is not software and software definitely not science.
    • jegp 3 hours ago
      Did you read the post...?
      • random3 1 hour ago
        Yes. It conflates a bunch of things

        > TL;DR I claim that modern science is synonymous with open source software

        That's a strong statement that's not supported by the arguments and IMO misguided.

        I don't have a problem with "open", but rather with "software".

        Both science and software deal with models, however the focus is quite different. I suspect you conflate theory with models.

        The goal of science is to produce and test theories — that's an inductive/abductive process. A model, regardless of whether it's reified into mathematical formulas or software, is a means of making a theory operational enough that its consequences can be derived and confronted with observations.

        Software often starts downstream of this: it's a reification of theories, models, algorithms, or findings that are the result of research. Of course software can also be used as part of the research process itself. The distinction is roughly the familiar one between research and development.

        • D-Machine 14 minutes ago
          I think it is worse than that. Science is a process for resolving disagreements, ambiguity, and uncertainty, and also for discovering abstractions (patterns) among phenomena. It is social and can not be reduced to a binary / digital file, as it is dynamic and ongoing, and, fundamentally, exploratory.

          Software is a static program and basically none of these things.

          Software development is kind of like science, in some ways, in that you discover abstractions and patterns, and this requires resolving disagreements and ambiguity between you and your users, but in the end, the user demands are usually fairly concrete and specific (though no one may know how to express those demands precisely, initially), and the process is not really exploratory in the way science is.

          It just really isn't a very good comparison IMO.

        • jegp 29 minutes ago
          Thank you for engaging. This is a much more insightful take.

          If I'm reading yiur argument right, you're saying that deployed models are downstream versions (reified) of aa theory. Theory, being the actual object of science.

          I think this misrepresents science. Science is the ability to build testable knowledge. From that,how would you separate the test from the science? In fact, in an ideal world, why wouldn't you want your theory to be put in a format that's executable? I'm not saying that those things are always the same, my (provocative) title is based on a dream where we can imagine theory and model coexist because software is now a thing.

      • jibal 2 hours ago
        https://news.ycombinator.com/newsguidelines.html

        > Please don't comment on whether someone read an article. "Did you even read the article? It mentions that" can be shortened to "The article mentions that".

        • jegp 46 minutes ago
          Arguments are fine. Vacuous statements need grounding. The follow-up is way more detailed
        • throwaway27448 2 hours ago
          [flagged]
  • throwaway27448 2 hours ago
    We really need to ban tech people from using the word "open".
    • jegp 14 minutes ago
      Erm. Why?
  • sarfaraznaushad 15 minutes ago
    [flagged]
  • marsven_422 54 minutes ago
    [dead]
  • jegp 4 hours ago
    TL;DR I claim that modern science is synonymous with open source software. This post explains why, why it matters, and what you can (and should) do next.
    • gradus_ad 3 hours ago
      What's the equivalent of closed source?
      • Matumio 1 hour ago
        Like if CERN published the discovery of the Higgs boson with 99.9997% certainty, but refusing to tell you how they calculated that number, or what equipment they used and how they calibrated it, in order to prevent other labs from copying their methods.

        Or like a machine learning lab claiming SOTA on a benchmark, beating a well-known method that they re-implemented, possibly with bugs, on their private dataset, for millions of compute. But you don't get the source to check, and they don't release any intermediate results or ablation experiments. Aka, from the outside you can't distinguish it from corporate marketing.

      • random3 3 hours ago
        It’s research happening privately without publishing, usually going into products
      • jegp 3 hours ago
        Equivalent? In the analogy of the math or physics results it would be a mental model in someone's brain that you can't access or verify. You just hope it's true
        • IanCal 2 hours ago
          Open source is much more than source available though. Its about licensing.
        • altmanaltman 47 minutes ago
          But that doesn't map to software at all right?
    • jibal 3 hours ago
      You argue that open software is science, which is not at all the same as claiming that science is software. ("is" in this context is not equivalence -- "a poodle is a dog" != "a dog is a poodle".)
      • jegp 2 hours ago
        I agree the post is muddy about whether the relationship is bijective (equivalent, poodle=dog) or injective (onto, poodle is a dog). I make it slightly more precise in the statement "I posit that open source software is a necessary condition if we are to science in a computerized world". That's where the "is" comes from in the title. Throughout history, this definitely has not been the case. I'm arguing that's changing.
        • jibal 2 hours ago
          It's not just "muddy", it's thoroughly inconsistent and impenetrable (which probably has a lot to do with why there is so little engagement here). You say "TL;DR I claim that modern science is synonymous with open source software" which is radically different from your "slightly more precise" statement.

          I won't put any more time into this ... good luck in figuring out what it is you really want to claim and presenting a coherent and cogent argument for it.

          • jegp 45 minutes ago
            Thanks for the well wishes